2017/2/21
The chemical name of benzofuran is benzo-2,1,3-oxadiazole, English name is benzofurazan, CAS number is 273-09-6, abbreviated as bfz. Its English name is benzofurazan or benzofurazan-1-oxide, CAS number is 480-96-6, abbreviated as BFO. Benzofurazan is also known as benzofurazan-1-oxide or benzo-2,1,3-oxadiazole-1-oxide.
By mixing, BFO is a very useful rubber promoter, which can reduce the hysteresis loss of vulcanizate filled with carbon black and reduce the viscosity of rubber.
In drug synthesis, BFO or bfz are important intermediates of quincetol, quinolone and tirazamine. Quincetate can improve feed utilization rate and has important antibacterial and growth promoting effects on pigs, sheep, fish and chickens. Quinolone is a safe, efficient and new feed additive. It can obviously promote the growth of animals, and the weight gain effect can reach 15% - 20%. Tirazamine, English name of tirazamine, is a very important anticancer drug. It can be reduced to a kind of metabolite with cytotoxic effect in tumor hypoxic cells, which makes the hypoxic cells in tumor tissue die.
4,6-dinitrobenzofuranoxan (dnbof) is an explosive with good thermal stability. The impact sensitivity and electrostatic spark sensitivity of dnbof are equivalent to RDX. The impact sensitivity of 7-amino-4,6-dinitrobenzofuran (adnbf) is equivalent to that of TNT. The impact sensitivity of 5,7-diamino-4,6-dinitrobenzofuran (cl-14) is lower than that of TNT, but the detonation velocity is higher.
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